2.4.1.206: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

This is an abbreviated version!
For detailed information about lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, go to the full flat file.

Reaction

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-, beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide synthase, beta1,3-N-acetylglucosaminyltransferase-2, beta1-3-N-acetylglucosaminyltransferase, beta3Gn-T2, beta3Gn-T5, beta3GnT5, GlcNAc transferase, LA2 synthase, LacCer(beta1,3)N-acetylglucosaminyltransferase, lactosylceramide beta-acetylglucosaminyltransferase, lactosylceramide: N-acetylglucosaminyltransferase, lactosylceramide:N-acetylglucosaminyltransferase, lactotriaosylceramide synthase, Lc2Cer-Glc-NAc-Tr, Lc3 synthase, Lc3 synthase/bGn-T5, UDP-GlcNAc:lactosylceramide beta1,3-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

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12	Activating Compound
11	AA Sequence
1	Application
1	CAS Registry Number
10	Cloned(Commentary)
37	Disease/ Diagnostics
8	General Information
1	Inhibitors
3	KM Value [mM]
4	Localization
7	Metals/Ions
14	Natural Substrates/ Products (Substrates)
157	Organism
4	Pathway
5	pH Optimum
1	pH Range
2	Protein Variants
1	Purification (Commentary)
1	Reaction
1	Reaction Type
17	Reference
61	Source Tissue
22	Specific Activity [micromol/min/mg]
40	Substrates and Products (Substrate)
26	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

KM Value

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KM Value on EC 2.4.1.206 - lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.021

D-galactosyl-1,4-beta-D-glucosylceramide

Rattus norvegicus

-

cerebellum microsomes

638232

0.035

D-galactosyl-1,4-beta-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide

Rattus norvegicus

-

cerebellum microsomes

638232

0.42

Galbeta(1->4)GlcNAcbeta1->2(Galbeta1->4GlcNAcbeta1->4)Manbeta1->3[Galbeta1->4GlcNAcbeta1->2(Galbeta1->4GlcNAcbeta1->6)Manbeta1->6]Manbeta1->4GlcNAc

Homo sapiens

-

betaGn3-T2

704447