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2.1.1.106: tryptophan 2-C-methyltransferase

This is an abbreviated version!
For detailed information about tryptophan 2-C-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
L-tryptophan
=
S-adenosyl-L-homocysteine
 +
L-2-methyltryptophan

Synonyms

S-adenosylmethionine:tryptophan 2-methyltransferase, thiostrepton A tryptophan methyltransferase, thiostrepton tryptophan methyltransferase, tryptophan 2-methyltransferase, TsrM, TsrT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.106 tryptophan 2-C-methyltransferase

Specific Activity

Specific Activity on EC 2.1.1.106 - tryptophan 2-C-methyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.6
substrate L-5-fluoro-tryptophan, pH 7.5, 25°C
1.2
substrate L-5-hydroxy-tryptophan, pH 7.5, 25°C
1.3
substrate L-5-methyl-tryptophan, pH 7.5, 25°C
3.5
cofactor hydroxycob(III)alamin, in presence of dithiothreitol, pH 7.5, 25°C
3.9
cofactor methylcob(III)alamin, pH 7.5, 25°C