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1.17.3.2: xanthine oxidase

This is an abbreviated version!
For detailed information about xanthine oxidase, go to the full flat file.

Word Map on EC 1.17.3.2

Reaction

xanthine
+
H2O
 +
O2
=
Urate
 +
H2O2

Synonyms

AXOR, EC 1.1.3.22, EC 1.2.3.2, EC 1.2.3.2., hypoxanthine oxidase, hypoxanthine-xanthine oxidase, hypoxanthine:oxygen oxidoreductase, More, oxidase, xanthine, Schardinger enzyme, xanthine dehydrogenase/oxidase, xanthine oxidase, xanthine oxidoreductase, xanthine: oxygen oxidoreductase, xanthine:O2 oxidoreductase, xanthine:oxygen oxidoreductase, xanthine:xanthine oxidase, XnOx, XO, XOD, XOR

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.3 With oxygen as acceptor
                1.17.3.2 xanthine oxidase

Specific Activity

Specific Activity on EC 1.17.3.2 - xanthine oxidase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0002 - 0.0022
-
enzyme activity in embryo cell lines
0.003
-
crude, cell-free liver enzyme extract
0.044
-
purified recombinant enzyme, substrate xanthine, pH 8.0
0.702
-
purified recombinant enzyme, substrate NADH, pH 6.6
1.67
-
-
1.712
-
purified recombinant enzyme, in presence of sulfide/dithionite
10.16
-
-
123
-
milk
17.5
-
pancreas enzyme with allopurinol at 50 mg/kg body weight
17.8
-
pancreas enzyme
189.6
-
electron acceptor O2
2.04
-
colostrum
2.4 - 5.1
-
-
2.963
-
-
25.2
-
intestine enzyme with allopurinol at 50 mg/kg body weight
26.6
-
intestine enzyme
29.5
-
kidney enzyme with allopurinol at 50 mg/kg body weight
4.7
-
cells grown at optimized conditions, pH 8.6, 37°C
49.9
-
kidney enzyme
51082.2
purified native enzyme, pH 7.6, 37°C
7.8
-
milk
8.571
-
-
800
-
electron acceptors O2 and NAD+
additional information