EC Number   |
Protein Variants |
Reference |
|---|
   3.2.2.6 | E226Q |
the mutation cripples enzymatic activity |
714921 |
| 3.2.2.6 | K120A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
732691 |
| 3.2.2.6 | more |
construction of CD38/NAD+ glycohydrolase truncated for the first 31 amino acids that encompass the transmembrane and short intracellular domains |
732691 |
| 3.2.2.6 | N100D |
site-directed mutagenesis, N-glycoylation at the site is abolished |
731119 |
| 3.2.2.6 | N164D |
site-directed mutagenesis, N-glycoylation at the site is abolished |
731119 |
| 3.2.2.6 | N209D |
site-directed mutagenesis, N-glycoylation at the site is abolished |
731119 |
| 3.2.2.6 | N219D |
site-directed mutagenesis, N-glycoylation at the site is abolished |
731119 |
| 3.2.2.6 | R216A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
732691 |
| 3.2.2.6 | S185A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
732691 |
| 3.2.2.6 | W118A |
site-directed mutagenesis, the mutant shows a decrease of the catalytic rate compared to the wild-type enzyme |
731357 |
