EC Number   |
Protein Variants |
Reference |
|---|
   3.2.2.6 | W118A/W181A |
site-directed mutagenesis, the mutant shows a decrease of the catalytic rate which is 16fold lower than the product of the effects of the two single mutations |
731357 |
| 3.2.2.6 | W118F |
site-directed mutagenesis, the mutant shows a decrease in activity compared to the wild-type enzyme |
731357 |
| 3.2.2.6 | W118H |
site-directed mutagenesis, the mutant shows a decrease in activity compared to the wild-type enzyme |
731357 |
| 3.2.2.6 | W168A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
732691 |
| 3.2.2.6 | W181A |
site-directed mutagenesis, the mutant shows a decrease of the catalytic rate and a reduced sensitivity to nicotinamide inhibition compared to the wild-type enzyme |
731357 |
| 3.2.2.6 | W181F |
site-directed mutagenesis, the mutant shows a decrease in activity and an increase in ADP cyclization compared to the wild-type enzyme |
731357 |
