EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.22.53 | Acidosis |
19251930 |
Influence of glutamine infusion on ubiquitin, caspase-3, cathepsins L and B, and m-calpain expression in sheep with nutritionally induced metabolic acidosis. |
ongoing research unassigned |
1 0 |
3.4.22.53 | Adenocarcinoma |
15466976 |
Overexpression of m-calpain in human colorectal adenocarcinomas. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 1 |
3.4.22.53 | Adenocarcinoma |
23329366 |
Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 4 1 |
3.4.22.53 | Alzheimer Disease |
1718565 |
Presence of calpain II immunoreactivity in senile plaques in Alzheimer's disease. |
causal interaction diagnostic usage ongoing research therapeutic application |
2 1 3 1 |
3.4.22.53 | Alzheimer Disease |
2072120 |
Comparison of Ca(2+)-activated proteinase enzyme and endogenous inhibitor activity in brain tissue from normal and Alzheimer's disease cases. |
diagnostic usage ongoing research unassigned |
3 4 0 |
3.4.22.53 | Alzheimer Disease |
9296555 |
Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. |
causal interaction ongoing research unassigned |
3 1 0 |
3.4.22.53 | Alzheimer Disease |
9654354 |
m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains. |
causal interaction ongoing research therapeutic application unassigned |
1 3 1 0 |
3.4.22.53 | Alzheimer Disease |
11516996 |
The calpain family and human disease. |
causal interaction diagnostic usage unassigned |
4 1 0 |
3.4.22.53 | Alzheimer Disease |
12070670 |
Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 2 2 2 |
3.4.22.53 | Alzheimer Disease |
23889979 |
Hypoxia-Triggered m-Calpain Activation Evokes Endoplasmic Reticulum Stress and Neuropathogenesis in a Transgenic Mouse Model of Alzheimer's Disease. |
ongoing research unassigned |
2 0 |