EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.4.53 | Acute Lung Injury |
15082290 |
Phosphodiesterase type 4 inhibitor prevents acute lung injury induced by cardiopulmonary bypass in a rat model. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 3.1.4.53 | Acute Lung Injury |
25019986 |
Blockade of PDE4B limits lung vascular permeability and lung inflammation in LPS-induced acute lung injury. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 3.1.4.53 | Acute Lung Injury |
26164036 |
Passive targeting of phosphatiosomes increases rolipram delivery to the lungs for treatment of acute lung injury: An animal study. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.1.4.53 | Acute Lung Injury |
28937238 |
Effects of roflumilast, a phosphodiesterase-4 inhibitor, on the lung functions in a saline lavage-induced model of acute lung injury. |
ongoing research
therapeutic application
unassigned |
4
3
0 |
| 3.1.4.53 | Acute Lung Injury |
34383981 |
Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.1.4.53 | Adenocarcinoma, Follicular |
9003417 |
Intracellular localization of the PDE4A cAMP-specific phosphodiesterase splice variant RD1 (RNPDE4A1A) in stably transfected human thyroid carcinoma FTC cell lines. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 3.1.4.53 | Adenoma |
11502813 |
Relevant cAMP-specific phosphodiesterase isoforms in human pituitary: effect of Gs(alpha) mutations. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
3
0 |
| 3.1.4.53 | Adenoma |
27267386 |
cAMP-specific PDE4 phosphodiesterases and AIP in the pathogenesis of pituitary tumors. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
4
0 |
| 3.1.4.53 | Adenoma |
29729370 |
Reduced protein expression of the phosphodiesterases PDE4A4 and PDE4A8 in AIP mutation positive somatotroph adenomas. |
causal interaction
ongoing research
unassigned |
1
2
0 |
| 3.1.4.53 | Adenoma |
30188895 |
The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
