EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   2.8.2.15 | 0.0006 |
- |
4-hydroxy-2',3,5-trichlorobiphenyl |
in 0.25 M potassium phosphate at pH 7.0, and 7.5 mM 2-mercaptoethanol, at 37°C |
724741 |
| 2.8.2.15 | 0.0007 |
- |
2,3-dichlorophenol |
IC50: 0.0007 mM, vs. 10 nM estradiol |
662863 |
| 2.8.2.15 | 0.0007 |
- |
2,4-Dichlorophenol |
IC50: 0.0007 mM, vs. 10 nM estradiol |
662863 |
| 2.8.2.15 | 0.0007 |
- |
quercetin |
IC50: 0.0007 mM, competitive |
661469 |
| 2.8.2.15 | 0.0008 |
- |
4'-hydroxy-2,3',4,5'-tetrachlorobiphenyl |
in 0.25 M potassium phosphate at pH 7.0, and 7.5 mM 2-mercaptoethanol, at 37°C |
724741 |
| 2.8.2.15 | 0.0012 |
- |
gavestinel |
isoform SULT1B1, using L-triiodothyronine as substrate, in 50 mM Tris/HCl buffer, pH 7.4, 1 mM dithiothreitol, 5 mM MgCl2, and 1 mg/ml bovine serum albumin, at 37°C |
702138 |
| 2.8.2.15 | 0.0016 |
- |
2,6-dichlorophenol |
IC50: 0.0016 mM, vs. 10 nM estradiol |
662863 |
| 2.8.2.15 | 0.0017 |
- |
endoxifen |
with dehydroepiandrosterone as substrate, at pH 7.4 and 37°C |
738099 |
| 2.8.2.15 | 0.0017 |
- |
gavestinel |
isoform SULT1B1, using xanthurenic acid as substrate, in 50 mM Tris/HCl buffer, pH 7.4, 1 mM dithiothreitol, 5 mM MgCl2, and 1 mg/ml bovine serum albumin, at 37°C |
702138 |
| 2.8.2.15 | 0.0022 |
- |
2,5-dichlorophenol |
IC50: 0.0022 mM, vs. 10 nM estradiol |
662863 |
