EC Number   |
Subunits |
Reference |
|---|
   3.4.22.55 | dimer |
1 * 13000 + 1 * ?, active form, SDS-PAGE |
664533 |
| 3.4.22.55 | dimer |
acive form, SDS-PAGE |
664882 |
| 3.4.22.55 | dimer |
active form |
663875 |
| 3.4.22.55 | dimer |
active form, 1 * 34000 + 1 * 18000, SDS-PAGE |
-, 664286 |
| 3.4.22.55 | dimer |
active form, SDS-PAGE |
664753 |
| 3.4.22.55 | dimer |
caspase-2 is activated by dimerization, initiator caspases are present in the cell as inactive monomers and their activation is promoted by dimerization. Dimerization results when initiator caspases are recruited to large molecular weight protein complexes that act as signaling platforms |
717458 |
| 3.4.22.55 | oligomer |
caspase-2 undergoes autocatalytic activation to remove the prodomain and linker region to generate a stable dimer consisting of the large subunit p19, residues 170-333, and the small subunit p12, residues 348-452. This p19/p12 dimer self-associates to form the active caspase-2 |
717846 |
| 3.4.22.55 | monomer |
inactive form |
663875 |
| 3.4.22.55 | monomer |
inactive form, 1 * 48000, SDS-PAGE |
-, 664286 |
| 3.4.22.55 | monomer |
inactive form, SDS-PAGE |
664882 |
