EC Number |
Subunits |
Reference |
---|
3.4.22.55 | ? |
x * 33000, active subunit |
713545 |
3.4.22.55 | ? |
x * 33000, isoform casp-2S, SDS-PAGE |
732733 |
3.4.22.55 | ? |
x * 45000, isoform casp-2L, SDS-PAGE |
732733 |
3.4.22.55 | ? |
x * 45000, SDS-PAGE |
731274 |
3.4.22.55 | dimer |
1 * 13000 + 1 * ?, active form, SDS-PAGE |
664533 |
3.4.22.55 | dimer |
acive form, SDS-PAGE |
664882 |
3.4.22.55 | dimer |
active form |
663875 |
3.4.22.55 | dimer |
active form, 1 * 34000 + 1 * 18000, SDS-PAGE |
-, 664286 |
3.4.22.55 | dimer |
active form, SDS-PAGE |
664753 |
3.4.22.55 | dimer |
caspase-2 is activated by dimerization, initiator caspases are present in the cell as inactive monomers and their activation is promoted by dimerization. Dimerization results when initiator caspases are recruited to large molecular weight protein complexes that act as signaling platforms |
717458 |