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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.1.3.36
microsome
-
-
134816
3.1.3.36
more
77% of the activity is localized in the particulate fraction
-
134812
3.1.3.36
more
OCRL1a is significantly more abundant in the cytoplasmic puncta, and there is less diffuse cytosolic staining compared to isoform b in NRK- and HeLa cells
-
693264
3.1.3.36
more
particulate fraction
-
134817
3.1.3.36
perinuclear space
-
-
678074
3.1.3.36
perinuclear space
both isoforms a and b predominantly localize to the perinuclear region
-
693264
3.1.3.36
Golgi membrane
cytoplasmic Golgi membrane
GO:0000139
AmiGO
QuickGO
652022
3.1.3.36
cell wall
-
GO:0005618
AmiGO
QuickGO
666576
3.1.3.36
nucleus
-
GO:0005634
AmiGO
QuickGO
751562
3.1.3.36
nucleus
in HuH-7 cells overexpressing SKIP and infected with hepatitis B virus (HBV), SKIP localizes to nucleus in addition to endoplasmic reticulum and suppresses HBV gene expression and replication. SKIP loses its nuclear localization and suppressive effect during replication of a core-negative HBV mutant
GO:0005634
AmiGO
QuickGO
691698
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