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Literature summary for 3.1.3.36 extracted from

  • Zhong, R.; Burk, D.H.; Morrison, W.H., 3rd; Ye, Z.H.
    FRAGILE FIBER3, an Arabidopsis gene encoding a type II inositol polyphosphate 5-phosphatase, is required for secondary wall synthesis and actin organization in fiber cells (2004), Plant Cell, 16, 3242-3259.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.36

Cloned(Commentary)

Cloned (Comment) Organism
gene fra3, expression pattern, DNA and amino acid sequence determination and analysis, complementation of an enzyme-deficient mutant Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of catalytically inactive fra3 missense mutants with an amino acid substitution in the conserved motif II of the catalytic domain, FRA3 overexpressing transgenic plants do not show a phenotype Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cell wall
-
 Arabidopsis thaliana 5618
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for activity, maximal activity at 3 mM Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O Arabidopsis thaliana the enzyme is involved in regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate levels in stem 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
-
 ?
additional information Arabidopsis thaliana the enzyme is essential in secondary cell wall synthesis in fiber cells and xylem vessels, enzyme deficiency causes a high reduction in secondary cell wall thickness and stem stability due to altered actin organization in fiber cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q84W55 gene fra3, i.e. FRAGILE FIBER3
-

Source Tissue

Source Tissue Comment Organism Textmining
fiber high expression of FRA3 Arabidopsis thaliana
-
stem inflorescence stems Arabidopsis thaliana
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vascular tissue
-
 Arabidopsis thaliana
-
xylem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O recombinant enzyme Arabidopsis thaliana 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O the enzyme is involved in regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate levels in stem Arabidopsis thaliana 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O preferred substrate of the recombinant enzyme Arabidopsis thaliana 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
-
 ?
1D-myo-inositol 1,4,5-trisphosphate + H2O recombinant enzyme Arabidopsis thaliana 1D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
additional information the enzyme is essential in secondary cell wall synthesis in fiber cells and xylem vessels, enzyme deficiency causes a high reduction in secondary cell wall thickness and stem stability due to altered actin organization in fiber cells Arabidopsis thaliana ?
-
 ?
additional information substrate specificity, no activity with 1D-myo-inositol 1,3,4,5-tetrakisphosphate, 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate, 1-phosphatidyl-1D-myo-inositol 5-phosphate, 1-phosphatidyl-1D-myo-inositol 4-phosphate, and 1-phosphatidyl-1D-myo-inositol 3-phosphate Arabidopsis thaliana ?
-
 ?

Subunits

Subunits Comment Organism
More the enzyme is composed of two domains, an N-terminal WD-repeat domain and a C-terminal catalytic domain Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
5PTase
-
 Arabidopsis thaliana
FRA3
-
 Arabidopsis thaliana
More cf. EC 3.1.3.56, inositol polyphosphate 5-phosphatase Arabidopsis thaliana
type II 5PTase
-
 Arabidopsis thaliana
type II inositol polyphosphate 5-phosphatase
-
 Arabidopsis thaliana

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
-
 Arabidopsis thaliana

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
22 37
-
 Arabidopsis thaliana

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 7.5
-
 Arabidopsis thaliana

pH Range

pH Minimum pH Maximum Comment Organism
5 9
-
 Arabidopsis thaliana