EC Number |
Activating Compound |
Reference |
---|
3.5.1.23 | 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate |
a bile salt analog |
667153 |
3.5.1.23 | adiponectin |
activates the ceramidase activity of adiponectin receptor ADIPOR2 about 20fold. Adiponectin is a hormone, secreted mainly from adipocytes, that stimulates glucose utilization and fatty-acid oxidation |
754889 |
3.5.1.23 | all-trans retinoic acid |
all-trans retinoic acid, ATRA, increases the expression of ACER2 in HeLa cells |
697862 |
3.5.1.23 | Ba2+ |
- |
171986 |
3.5.1.23 | cAMP-responsive element binding protein |
CREB is a central regulator os ASAH1 gene transcription |
696443 |
3.5.1.23 | cardiolipin |
- |
712031 |
3.5.1.23 | cardiolipin |
activates the ceramidase activity by 2.5fold at 8-10 mol%, inhibits the ceramide synthesis activity, mechanism |
655998 |
3.5.1.23 | cardiolipin |
phosphatidylglycerol and cardiolipin, which are major lipid components of Staphylococcus aureus, are effective in stimulating the hydrolysis of human skin-type ceramides in the absence of detergents |
733408 |
3.5.1.23 | ceramide-1-phosphate |
activates neutral ceramidase |
719197 |
3.5.1.23 | ceramide-1-phosphate |
stimulates |
654614 |