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Information on EC 3.1.3.100 - thiamine phosphate phosphatase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.100 thiamine phosphate phosphatase
IUBMB Comments
The enzyme participates in the thiamine biosynthesis pathway in eukaryotes and a few prokaryotes. These organisms lack EC 2.7.4.16, thiamine-phosphate kinase, and need to convert thiamine phosphate to thiamine diphosphate, the active form of the vitamin, by first removing the phosphate group, followed by diphosphorylation by EC 2.7.6.2, thiamine diphosphokinase.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
thiamin-binding protein, thiamine-repressible acid phosphatase, tdp/tmp phosphatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
thiamine phosphate + H2O = thiamine + phosphate
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