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Information on EC 2.5.1.68 - (2Z,6E)-farnesyl diphosphate synthase

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IUBMB Comments
Requires Mg2+ or Mn2+ for activity. The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan. Neryl diphosphate can also act as substrate.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
rv1086, z-farnesyl diphosphate synthase, cis-farnesyl diphosphate synthase, z,e-fpp synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)-farnesyl diphosphate
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