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Information on EC 1.1.1.271 - GDP-L-fucose synthase

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EC Tree
     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.271 GDP-L-fucose synthase
IUBMB Comments
Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
fx protein, gdp-fucose synthetase, gdp-4-keto-6-deoxy-d-mannose epimerase/reductase, gdp-4-keto-6-deoxy-d-mannose-3,5-epimerase-4-reductase, gdp-keto-6-deoxymannose 3,5-epimerase/4-reductase, gdp-fucose synthase, gdp-4-keto-6-deoxy-d-mannose-3,5-epimerase/reductase, gdp-l-fucose synthetase, transplantation antigen p35b, red cell nadp(h)-binding protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GDP-beta-L-fucose + NADP+ = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H+
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