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EC 2.7.1.223 Details
EC number
2.7.1.223
Accepted name
aminoimidazole riboside kinase
Reaction
ATP + 5-amino-1-(β-D-ribosyl)imidazole = ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole
Other name(s)
STM4066 (locus name)
Systematic name
ATP:5-amino-1-(β-D-ribosyl)imidazole 5′-phosphotransferase
Comment
The enzyme, characterized from the bacterium Salmonella enterica, can phosphorylate exogeneously-provided 5-amino-1-(β-D-ribosyl)imidazole to form 5-amino-1-(5-phospho-β-D-ribosyl)imidazole (AIR), an important intermediate in the production of both purine mononucleotides and the hydroxymethyl pyrimidine moiety of thiamine.
History
created 2018
EC Tree
2.7.1.9 created 1961, deleted 1965
2.7.1.57 created 1972, deleted 1984
2.7.1.70 created 1972, deleted 2004
2.7.1.75 created 1972, deleted 1976
2.7.1.96 created 1978, deleted 1978
2.7.1.97 created 1978, deleted 1992
2.7.1.98 created 1978, deleted 1984
2.7.1.111 created 1984, deleted 1992
2.7.1.133 created 1990, deleted 2002
2.7.1.139 created 1992, deleted 2002
2.7.1.152 created 2002, deleted 2003