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EC 2.7.1.120 Details
EC number
2.7.1.120
Accepted name
caldesmon kinase
Reaction
ATP + caldesmon = ADP + caldesmon phosphate
Other name(s)
caldesmon kinase (phosphorylating)
Systematic name
ATP:caldesmon O-phosphotransferase
CAS registry number
93229-57-3
Comment
Requires Ca2+ and calmodulin. Phosphorylation abolishes the ability of the protein caldesmon to bind actin and inhibit ATPase. The enzyme appears to be identical with caldesmon; the reaction is an autophosphorylation.
History
created 1989, modified 1990, deleted 2005
EC Tree
2.7.1.9 created 1961, deleted 1965
2.7.1.57 created 1972, deleted 1984
2.7.1.70 created 1972, deleted 2004
2.7.1.75 created 1972, deleted 1976
2.7.1.96 created 1978, deleted 1978
2.7.1.97 created 1978, deleted 1992
2.7.1.98 created 1978, deleted 1984
2.7.1.111 created 1984, deleted 1992
2.7.1.133 created 1990, deleted 2002
2.7.1.139 created 1992, deleted 2002
2.7.1.152 created 2002, deleted 2003