EC Explorer

2.7.10.2

non-specific protein-tyrosine kinase

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

ABL, ABL1, ABL2, ABLL, ACK1, ACK2, AGMX1, ARG, ATK, ATP:protein-tyrosine O-phosphotransferase (ambiguous), BLK, Bmk, BMX, BRK, Bruton’s tyrosine kinase, Bsk, BTK, BTKL, CAKb, Cdgip, CHK, CSK, CTK, CYL, cytoplasmic protein tyrosine kinase, EMT, ETK, Fadk, FAK, FAK2, FER, Fert1/2, FES, FGR, focal adhesion kinase, FPS, FRK, FYN, HCK, HCTK, HYL, IMD1, ITK, IYK, JAK1, JAK2, JAK3, Janus kinase 1, Janus kinase 2, Janus kinase 3, JTK1, JTK9, L-JAK, LCK, LSK, LYN, MATK, Ntk, p60c-src protein tyrosine kinase, PKB, protein-tyrosine kinase (ambiguous), PSCTK, PSCTK1, PSCTK2, PSCTK4, PSCTK5, PTK2, PTK2B, PTK6, PYK2, RAFTK, RAK, Rlk, Sik, SLK, SRC, SRC2, SRK, SRM, SRMS, STD, SYK, SYN, Tck, TEC, TNK1, Tsk, TXK, TYK2, TYK3, YES1, YK2, ZAP70

ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)

Unlike EC 2.7.10.1, receptor protein-tyrosine kinase, this protein-tyrosine kinase does not have a transmembrane domain. In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into ten families [1].

created 1984 as EC 2.7.1.112, part transferred 2005 to EC 2.7.10.2