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EC 1.3.3.10 Details
show Brenda entryEC number
1.3.3.10
Accepted name
tryptophan α,β-oxidase
Reaction
L-tryptophan + O2 = α,β-didehydrotryptophan + H2O2
Other name(s)
L-tryptophan 2′,3′-oxidase,
L-tryptophan α,β-dehydrogenase
Systematic name
L-tryptophan:oxygen α,β-oxidoreductase
CAS registry number
156859-19-7
Comment
Requires heme. The enzyme from Chromobacterium violaceum is specific for tryptophan derivatives possessing its carboxyl group free or as an amide or ester, and an unsubstituted indole ring. Also catalyses the α,β dehydrogenation of L-tryptophan side chains in peptides. The product of the reaction can hydrolyse spontaneously to form (indol-3-yl)pyruvate.
History
created 2000 as EC 1.4.3.17, transferred 2003 to EC 1.3.3.10
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002 1.1.99.15 created 1978, deleted 1980 1.1.99.17 created 1982, deleted 2003 1.3.3.2 created 1972, deleted 2005
