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Information on EC 1.3.3.10 - tryptophan alpha,beta-oxidase

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EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.10 tryptophan alpha,beta-oxidase
IUBMB Comments
Requires heme. The enzyme from Chromobacterium violaceum is specific for tryptophan derivatives possessing its carboxyl group free or as an amide or ester, and an unsubstituted indole ring. Also catalyses the alpha,beta dehydrogenation of L-tryptophan side chains in peptides. The product of the reaction can hydrolyse spontaneously to form (indol-3-yl)pyruvate.
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The enzyme appears in viruses and cellular organisms
Synonyms
l-tryptophan 2',3'-oxidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2
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