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EC 3.5.99.9 Details

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EC number

3.5.99.9

Accepted name

2-nitroimidazole nitrohydrolase

Reaction

2-nitroimidazole + H₂O = imidazol-2-one + nitrite

Other name(s)

NnhA, 2NI nitrohydrolase, 2NI denitrase

Systematic name

2-nitroimidazole nitrohydrolase

Comment

The enzyme catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp. JS330

History

created 2012

EC Tree

1 Oxidoreductases

2 Transferases

3 Hydrolases

3.1 Acting on ester bonds

3.2 Glycosylases

3.3 Acting on ether bonds

3.4 Acting on peptide bonds (peptidases)

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.2 In cyclic amides

3.5.3 In linear amidines

3.5.4 In cyclic amidines

3.5.5 In nitriles

3.5.99 In other compounds

3.5.99.1 riboflavinase

3.5.99.2 aminopyrimidine aminohydrolase

3.5.99.3 hydroxydechloroatrazine ethylaminohydrolase

3.5.99.4 N-isopropylammelide isopropylaminohydrolase

3.5.99.5 2-aminomuconate deaminase

3.5.99.6 glucosamine-6-phosphate deaminase

3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase

3.5.99.8 5-nitroanthranilic acid aminohydrolase

3.5.99.9 2-nitroimidazole nitrohydrolase

3.5.99.10 2-iminobutanoate/2-iminopropanoate deaminase

3.5.99.11 2-aminomuconate deaminase (2-hydroxymuconate-forming)

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.2 In sulfonyl-containing anhydrides

3.6.3 Acting on acid anhydrides to catalyse transmembrane movement of substances

3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement

3.6.4.1 myosin ATPase

3.6.4.2 dynein ATPase

3.6.4.3 microtubule-severing ATPase

3.6.4.4 plus-end-directed kinesin ATPase

3.6.4.5 minus-end-directed kinesin ATPase

3.6.4.6 vesicle-fusing ATPase

3.6.4.7 peroxisome-assembly ATPase

3.6.4.8 proteasome ATPase

3.6.4.9 chaperonin ATPase

3.6.4.10 non-chaperonin molecular chaperone ATPase

3.6.4.11 nucleoplasmin ATPase

3.6.4.12 DNA helicase

3.6.4.13 RNA helicase

3.6.5 Acting on GTP to facilitate cellular and subcellular movement

3.7 Acting on carbon-carbon bonds

3.8 Acting on halide bonds

3.9 Acting on phosphorus-nitrogen bonds

3.10 Acting on sulfur-nitrogen bonds

3.11 Acting on carbon-phosphorus bonds

3.12 Acting on sulfur-sulfur bonds

3.13 Acting on carbon-sulfur bonds