EC Explorer

3.5.99.2

aminopyrimidine aminohydrolase

(1) 4-amino-5-aminomethyl-2-methylpyrimidine + H₂O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH₃;;(2) thiamine + H₂O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole

thiaminase (ambiguous), thiaminase II, tenA (gene name)

4-amino-5-aminomethyl-2-methylpyrimidine aminohydrolase

9024-80-0

Previously known as thiaminase II, this enzyme is involved in the regeneration of the thiamine pyrimidine from degraded products, rather than in thiamine degradation, and participates in thiamine salvage pathways.

created 1961, modified 2011