EC Explorer
[browse EC tree] - [search]
EC 2.3.1.185 Details
show Brenda entryEC number
2.3.1.185
Accepted name
tropine acyltransferase
Reaction
an acyl-CoA + tropine = CoA + an O-acyltropine
Other name(s)
tropine:acyl-CoA transferase,
acetyl-CoA:tropan-3-ol acyltransferase,
tropine acetyltransferase,
tropine tigloyltransferase,
TAT
Systematic name
acyl-CoA:tropine O-acyltransferase
CAS registry number
138440-79-6, 162535-29-7
Comment
This enzyme exhibits absolute specificity for the endo/3α configuration found in tropine as pseudotropine (tropan-3β-ol; see EC 2.3.1.186, pseudotropine acyltransferase) is not a substrate [3]. Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-CoA and acetyl-CoA being the best substrates. It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine [4].
History
created 2008
back to topEC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
