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Information on EC 2.3.1.185 - tropine acyltransferase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.185 tropine acyltransferase
IUBMB Comments
This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine (tropan-3beta-ol; see EC 2.3.1.186, pseudotropine acyltransferase) is not a substrate . Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl-CoA and acetyl-CoA being the best substrates. It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine .
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The enzyme appears in viruses and cellular organisms
Synonyms
tropine:acyl-coa transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an acyl-CoA + tropine = CoA + an O-acyltropine
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