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4.2.1.70: pseudouridylate synthase

This is an abbreviated version!
For detailed information about pseudouridylate synthase, go to the full flat file.

Word Map on EC 4.2.1.70

Reaction

Uracil
+
D-ribose 5-phosphate
=
pseudouridine 5'-phosphate
+
H2O

Synonyms

16S pseudouridine 516 synthase, 16S pseudouridylate 516 synthase, 5-ribosyluracil 5'-phosphate synthetase, Depressed growth-RATE protein DEG1, IndA, More, ORP protein, Osmoprotectant regulator of PLC, P35 protein, pseudouridine monophosphate synthetase, pseudouridine synthase, pseudouridine synthase I, pseudouridine-5'-phosphate glycosidase, Pseudouridylate synthase, pseudouridylate synthetase, pseudouridylate synthetase I, pseudouridylate synthetase II, pseudouridylic acid synthetase, PSI55 synthase, psi55 tRNA pseudouridine synthase, psiMP synthetase, psisynthetase, psiUMP synthetase, PSUI, PUS, synthase, pseudouridylate, tRNA pseudouridine 55 synthase, TruB, uracil hydrolyase, YeiN

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.70 pseudouridylate synthase

Metals Ions

Metals Ions on EC 4.2.1.70 - pseudouridylate synthase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Co2+
high activity
Fe2+
high activity
Mg2+
-
required, broad maximal activity between 0.01 M and 0.05 M
Mn2+
high activity
Zn2+
-
essential for its native conformation and tRNA recognition
additional information