4.2.1.70: pseudouridylate synthase
This is an abbreviated version!
For detailed information about pseudouridylate synthase, go to the full flat file.
Word Map on EC 4.2.1.70
-
4.2.1.70
-
pseudouridylation
-
baculovirus
-
ribonucleoproteins
-
congenita
-
dyskeratosis
-
dyskerin
-
rna-guided
-
snornps
-
rna-modifying
-
sideroblastic
-
roscovitine
-
archaeosine
-
gar1
-
nop10
-
his
- 4.2.1.70
-
pseudouridylation
-
baculovirus
- ribonucleoproteins
- congenita
-
dyskeratosis
-
dyskerin
-
rna-guided
-
snornps
-
rna-modifying
-
sideroblastic
- roscovitine
-
archaeosine
- gar1
- nop10
- his
Reaction
Synonyms
16S pseudouridine 516 synthase, 16S pseudouridylate 516 synthase, 5-ribosyluracil 5'-phosphate synthetase, Depressed growth-RATE protein DEG1, IndA, More, ORP protein, Osmoprotectant regulator of PLC, P35 protein, pseudouridine monophosphate synthetase, pseudouridine synthase, pseudouridine synthase I, pseudouridine-5'-phosphate glycosidase, Pseudouridylate synthase, pseudouridylate synthetase, pseudouridylate synthetase I, pseudouridylate synthetase II, pseudouridylic acid synthetase, PSI55 synthase, psi55 tRNA pseudouridine synthase, psiMP synthetase, psisynthetase, psiUMP synthetase, PSUI, PUS, synthase, pseudouridylate, tRNA pseudouridine 55 synthase, TruB, uracil hydrolyase, YeiN
ECTree
4.2.1.70 pseudouridylate synthaseAdvanced search results
results (
results (Reference
top
Reference on EC 4.2.1.70 - pseudouridylate synthase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Heinrikson, R.L.; Goldwasser, E.
Studies on the biosynthesis of 5-ribosyluracil 5'-monophosphate in Tetrahymena pyriformis
J. Biol. Chem.
239
1177-1187
1964
Tetrahymena pyriformis
Suzuki, T.; Hochster, R.M.
On the biosynthesis of pseudouridine and of pseudouridylic acid in Agrobacterium tumefaciens
Can. J. Biochem.
44
259-272
1966
Agrobacterium tumefaciens
Breitman, T.R.
Pseudouridylate synthetase of Escherichia coli: correlation of its activity with utilization of pseudouridine for growth
J. Bacteriol.
103
263-264
1970
Escherichia coli
Salomon, L.R.; Breitman, T.R.
Pseudouridylate synthetase of Escherichia coli: a catabolite-repressible enzyme
J. Bacteriol.
107
535-542
1971
Escherichia coli
Matsushita, T.; Davis, F.F.
Studies on pseudouridylic acid synthetase from various sources
Biochim. Biophys. Acta
238
165-173
1971
Agrobacterium tumefaciens, Bos taurus, Brassica oleracea, Saccharomyces cerevisiae, Lolium perenne, Nicotiana glauca, Spinacia oleracea, Agrobacterium tumefaciens B6-6
Remsen, J.F.; Matsushita, T.; Chirikjian, J.G.; Davis, F.F.
Enzymatic synthesis of deoxypseudouridylic acid an a study of certain of its properties
Biochim. Biophys. Acta
281
481-487
1972
Agrobacterium tumefaciens, Escherichia coli, Tetrahymena pyriformis, Agrobacterium tumefaciens ATCC 15955
Kalman, T.I.
Enzymatic synthesis of 2'-deoxypseudouridylic acid
Biochem. Biophys. Res. Commun.
46
1194-1200
1972
Agrobacterium tumefaciens, Salmonella enterica subsp. enterica serovar Typhimurium, Tetrahymena pyriformis
Ciampi, M.S.; Arena, F.; Cortese, R.
Biosynthesis of pseudouridine in the in vitro transcribed tRNATyr precursor
FEBS Lett.
77
75-82
1977
Salmonella enterica subsp. enterica serovar Typhimurium
Bruni, C.B.; Colantuoni, V.; Sbordone, L.; Cortese, R.; Blasi, F.
Biochemical and regulatory properties of Escherichia coli K-12 hisT mutants
J. Bacteriol.
130
4-10
1977
Escherichia coli
Arena, F.; Ciliberto, G.; Ciampi, S.; Cortese, R.
Purification of pseudouridylate synthetase I from Salmonella typhimurium
Nucleic Acids Res.
5
4523-4536
1978
Salmonella enterica subsp. enterica serovar Typhimurium
Frendewey, D.A.; Kladianos, D.M.; Moore, V.G.; Kaiser, I.I.
Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli
Biochim. Biophys. Acta
697
31-40
1982
Escherichia coli
Marvel, C.C.; Arps, P.J.; Rubin, B.C.; Kammen, H.O.; Penhoet, E.E.; Winkler, M.E.
HisT is part of a multigene operon in Escherichia coli K-12
J. Bacteriol.
161
60-71
1985
Escherichia coli
Searles, L.L.; Jones, J.W.; Fournier, M.J.; Grambow, N.; Tyler, B.; Calvo, J.M.
Escherichia coli B/r leuK mutant lacking pseudouridine synthase I
J. Bacteriol.
166
341-345
1986
Escherichia coli, Escherichia coli EB146 (leuK16)
Arps, P.J.; Winkler, M.E.
An unusual genetic link between vitamin B6 biosynthesis and tRNA pseudouridine modification in Escherichia coli K-12
J. Bacteriol.
169
1071-1079
1987
Escherichia coli
Arps, P.J.; Winkler, M.E.
Structural analysis of the Escherichia coli K-12 hisT operon by using a kanamycin resistance cassette
J. Bacteriol.
169
1061-1070
1987
Escherichia coli
Negre, D.; Cortay, J.C.; Donini, P.; Cozzone, A.J.
Inaccurate protein synthesis in a mutant of Salmonella typhimurium defective in transfer RNA pseudouridylation
FEBS Lett.
234
165-168
1988
Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium TA997
Motorin, Y.; Keith, G.; Simon, C; Foiret, D.; Simos, G.; Hurt, E.; Grosjean, H.
The yeast tRNA: pseudouridine synthase Pus1p displays a multisite substrate specificity
RNA
4
856-869
1998
Saccharomyces cerevisiae
Arluison, V.; Hountondji, C.; Robert, B.; Grosjean, H.
Transfer RNA-Pseudouridine Synthetase Pus1 of Saccharomyces cerevisiae contains one atom of zinc essential for its native conformation and tRNA recognition
Biochemistry
37
7268-7276
1998
Saccharomyces cerevisiae
Corollo, D.; Blair-Johnson, M.; Conrad, J.; Friedler, T.; Sun, D.; Wang, L.; Ofengand, J.; Fenna, R.
Crystallisation and characterization of a fragment of pseudouridine synthase RluC from Escherichia coli
Acta Crystallogr. Sect. D
55
302-304
1999
Escherichia coli
-
Massenet, S.; Motorin, Y.; Lafontaine, D.L.J.; Hurt, E.; Grosjean, H.; Branlant, C.
Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase Pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA
Mol. Cell. Biol.
19
2142-2154
1999
Saccharomyces cerevisiae, Saccharomyces cerevisiae FL100
Chen, J.; Patton, J.R.
Cloning and characterization of a mammalian pseudouridine synthase
RNA
5
409-419
1999
Escherichia coli, Mus musculus
Arluison, V.; Buckle, M.; Grosjean, H.
Pseudouridine synthetase Pus1 of Saccharomyces cerevisiae: kinetic characterisation, tRNA structural requirement and real-time analysis of its complex with tRNA
J. Mol. Biol.
289
491-502
1999
Saccharomyces cerevisiae
Foster, P.G.; Huang, L.; Santi, D.; Stroud, R.
The structural basis of tRNA recognition and pseudouridine formation by pseudouridine synthase I
Nat. Struct. Biol.
7
23-27
2000
Escherichia coli
Chen, J.; Patton, J.
Mouse pseudouridine synthase I: gene structure and alternative splicing of pre-mRNA
Biochem. J.
352
465-473
2000
Mus musculus (Q9WU56), Mus musculus
Patton, J.; Padgett, R.
Caenorhabditis elegans pseudouridine synthase I activity in vivo: tRNA is a substrate but not U2 small nuclear RNA
Biochem. J.
372
595-602
2003
Caenorhabditis elegans, Caenorhabditis elegans N1
Wouters, J.; Tricot, C.; Durbecq, V.; Roovers, M.; Stalon, V.; Droogmans, L.
Preliminary X-ray crystallographic analysis of tRNA pseudouridine 55 synthase from the thermophilic eubacterium Thermotoga maritima
Acta Crystallogr. Sect. D
59
152-154
2003
Escherichia coli, Thermotoga maritima, Thermotoga maritima MSB8 / DSM 3109 / ATCC 43589, Escherichia coli TruB
Del Campo, M.; Ofengand, J.; Malhotra, A.
Purification and crystallization of Escherichia coli pseudouridine synthase RluD
Acta Crystallogr. Sect. D
59
1871-1873
2003
Escherichia coli, Escherichia coli RluD
Ericsson, U.B.; Andersson, M.E.; Engvall, B.; Nordlund, P.; Hallberg, B.M.
Expression, purification, crystallization and preliminary diffraction studies of the tRNA pseudouridine synthase TruD from Escherichia coli
Acta Crystallogr. Sect. D
60
775-776
2004
Escherichia coli
Chen, J.; Patton, J.R.
Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA
Biochemistry
39
12723-12730
2000
Mus musculus (Q9JI38)
Hoang, C.; Ferre-D'Amare, A.R.
Cocrystal structure of a tRNA psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme
Cell
107
929-939
2001
Escherichia coli, Escherichia coli TruB
Kaya, Y.; Del Campo, M.; Ofengand, J.; Malhotra, A.
Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold
J. Biol. Chem.
279
18107-18110
2004
Escherichia coli
Chaudhuri, B.N.; Chan, S.; Perry, L.J.; Yeates, T.O.
Crystal structure of the apo forms of psi55 tRNA pseudouridine synthase from Mycobacterium tuberculosis. A hinge at the base of the catalytic cleft
J. Biol. Chem.
279
24585-24591
2004
Mycobacterium tuberculosis, Mycobacterium tuberculosis TruB
Sivaraman, J.; Iannuzzi, P.; Cygler, M.; Matte, A.
Crystal structure of the RluD pseudouridine synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli
J. Mol. Biol.
335
87-101
2004
Escherichia coli, Escherichia coli RluD
Sivaraman, J.; Sauve, V.; Larocque, R.; Stura, E.A.; Schrag, J.D.; Cygler, M.; Matte, A.
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP
Nat. Struct. Biol.
9
353-358
2002
Escherichia coli, Escherichia coli RsuA
Ansmant, I.; Massenet, S.; Grosjean, H.; Motorin, Y.; Branlant, C.
Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi2819 in 21S mitochondrial ribosomal RNA
Nucleic Acids Res.
28
1941-1946
2000
Saccharomyces cerevisiae (Q06244)
Phannachet, K.; Huang, R.H.
Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
Nucleic Acids Res.
32
1422-1429
2004
Thermotoga maritima, Thermotoga maritima psi55S
Pan, H.; Agarwalla, S.; Moustakas, D.T.; Finer-Moore, J.; Stroud, R.M.
Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit
Proc. Natl. Acad. Sci. USA
100
12648-12653
2003
Escherichia coli, Thermotoga maritima, Thermotoga maritima TruB, Escherichia coli TruB
Gu, X.; Liu, Y.; Santi, D.V.
The mechanism of pseudouridine synthase I as deduced from its interaction with 5-fluorouracil-tRNA
Proc. Natl. Acad. Sci. USA
96
14270-14275
1999
Escherichia coli
Preumont, A.; Snoussi, K.; Stroobant, V.; Collet, J.F.; Van Schaftingen, E.
Molecular identification of pseudouridine-metabolizing enzymes
J. Biol. Chem.
283
25238-25246
2008
Thermotoga maritima, Escherichia coli (P33025), Escherichia coli
Wright, J.R.; Keffer-Wilkes, L.C.; Dobing, S.R.; Kothe, U.
Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis
RNA
17
2074-2084
2011
Escherichia coli
html completed
