3.5.1.65: theanine hydrolase

This is an abbreviated version!
For detailed information about theanine hydrolase, go to the full flat file.

Reaction

N5-Ethyl-L-glutamine
+
H2O
=
L-glutamate
+
ethylamine

Synonyms

L-theanine hydrolase, L-theanine hydrolyzing enzyme, theanine hydrolyzing enzyme, theanine hydrolytic enzyme, theanine ethylamidohydrolase, hydrolase, theanine

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.65 theanine hydrolase

Substrates Products

Substrates Products on EC 3.5.1.65 - theanine hydrolase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-glutamine + H2O
D-glutamate + NH3
show the reaction diagram
-
-
-
-
?
L-glutamine + H2O
L-glutamate + NH3
show the reaction diagram
-
-
-
-
?
N5-ethyl-D-glutamine + H2O
D-glutamate + ethylamine
show the reaction diagram
-
D-theanine, probably by the same enzyme like L-theanine
-
?
N5-ethyl-L-glutamine + H2O
L-glutamate + ethylamine
show the reaction diagram
N5-isobutyl-L-glutamine + H2O
L-glutamate + isobutylamine
show the reaction diagram
-
gamma-glutamyl-isobutylamide, 136% of activity compared to L-theanine
-
-
?
N5-methyl-L-glutamine + H2O
L-glutamate + methylamine
show the reaction diagram
-
gamma-glutamylmethylamide, 77% of activity compared to L-theanine
-
-
?
N5-n-butyl-L-glutamine + H2O
L-glutamate + n-butylamine
show the reaction diagram
-
gamma-glutamyl-n-butylamide, 276% of activity compared to L-theanine
-
-
?
N5-n-pentyl-L-glutamine + H2O
L-glutamate + n-pentylamine
show the reaction diagram
-
gamma-glutamyl-n-amylamide, 211% of activity compared to L-theanine
-
-
?
N5-n-propyl-L-glutamine + H2O
L-glutamate + n-propylamine
show the reaction diagram
-
gamma-glutamyl-n-propylamide, 144% of activity compared to theanine
-
-
?
theanine + hydroxylamine
gamma-glutamylhydroxamic acid + ethylamine
show the reaction diagram
-
transferase reaction
-
-
?
additional information
?
-