3.5.1.32: hippurate hydrolase
This is an abbreviated version!
For detailed information about hippurate hydrolase, go to the full flat file.
Reaction
hippurate +
H2O=
benzoate +
glycine
Synonyms
Benzoylglycine amidohydrolase, hippurate hydrolase, hippuricase
ECTree
Inhibitors
Inhibitors on EC 3.5.1.32 - hippurate hydrolase
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1,10-phenanthroline
-
99% inhibition at 0.5 mM
2,2'-dipyridyl
-
80% inhibition at 1 mM
2-mercaptoethanol
-
20% inhibition at 2 mM
8-hydroxyquinoline
-
60% inhibition at 3.3 mM
Ag+
-
98% inhibition at 2 mM
Ba2+
-
slight inhibition at 1 mM
Cd2+
-
65% inhibition at 2 mM
EDTA
-
40% inhibition at 10 mM
Fe3+
-
42% inhibition at 1 mM
Mn2+
-
60% inhibition at 1 mM
o-phenanthroline
-
complete inhibition at 1 mM
p-chloromercuribenzoic acid
Zn2+
-
35% inhibition at 2 mM
additional information
-
no significant inhibition by E64, PMSF, and pepstatin at 0.5 mM
-
Ag2+
-
complete inhibition at 1 mM
Ag2+
-
complete inhibition at 1 mM
Ca2+
-
55% inhibition at 2 mM
Ca2+
-
slight inhibition at 1 mM
Co2+
-
70% inhibition at 2 mM
Co2+
-
slight inhibition at 1 mM
Co2+
-
slight inhibition at 1 mM
Cu2+
-
78% inhibition at 2 mM
Cu2+
-
complete inhibition at 1 mM
Cu2+
-
complete inhibition at 1 mM
Fe2+
-
-
Fe2+
-
80% inhibition at 1 mM
Hg2+
-
82% inhibition at 1 mM
Hg2+
-
complete inhibition at 1 mM
iodoacetic acid
-
20% inhibition at 10 mM
iodoacetic acid
-
60% inhibition at 1 mM
Ni2+
-
65% inhibition at 2 mM
Ni2+
-
complete inhibition at 1 mM
p-chloromercuribenzoic acid
-
complete inhibition at 1 mM
p-chloromercuribenzoic acid
-
complete inhibition at 1 mM
3.5.1.32 hippurate hydrolase
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