3.5.1.136: N,N'-diacetylchitobiose non-reducing end deacetylase

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For detailed information about N,N'-diacetylchitobiose non-reducing end deacetylase, go to the full flat file.

Reaction

beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine

Synonyms

CDA, Dac, diacetylchitobiose deacetylase, N,N'-diacetylchitobiose deacetylase, NAc2 deacetylase, PH0499, Tk-Dac

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.136 N,N'-diacetylchitobiose non-reducing end deacetylase

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Results	in table
3	AA Sequence
8	Application
7	Cloned(Commentary)
4	Crystallization (Commentary)
1	Expression
1	Inhibitors
3	kcat/KM [mM/s]
5	KM Value [mM]
1	Localization
1	Metals/Ions
2	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
44	Organism
1	Pathway
2	pH Optimum
10	Protein Variants
5	Purification (Commentary)
1	Reaction
17	Reference
36	Substrates and Products (Substrate)
15	Subunits
24	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 3.5.1.136 - N,N'-diacetylchitobiose non-reducing end deacetylase

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N,N'-diacetylchitobiose non-reducing end acetylhydrolase

The enzyme, characterized from the archaeons Thermococcus kodakarensis and Pyrococcus horikoshii, deacetylates the non-reducing residue of N,N'-diacetylchitobiose, the end product of the archaeal chitinase, to produce beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine. This is in contrast to EC 3.5.1.105, chitin disaccharide deacetylase, which deacetylates N,N'-diacetylchitobiose at the reducing residue to produce N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine.