3.4.21.55: Venombin AB

casein + H2O

hydrolyzed casein

coagulation factor VIII + H2O

moderate activity

collagen alpha-2(I) chain + H2O

moderate activity

Fibrin alpha-chain + H2O

Hydrolyzed fibrin alpha-chain

fragments of low molecular mass

Fibrinogen + H2O

2 entries

Fibrinogen + H2O

Fibrinopeptide A + fibrinopeptide B + ?

3 entries

FSARGHRP + H2O

a peptide derived from human fibrinogen beta-chain

H-D-Cyclohexylglycyl-L-2-aminobutyryl-L-arginine 4-nitroanilide + H2O

H-D-Cyclohexylglycyl-L-alpha-aminobutyryl-L-arginine + 4-nitroaniline

i.e. CBS 34-47, chromogenic substrate

H-D-Hexahydrotyrosyl-Ala-Arg 4-nitroanilide + H2O

H-D-phenylglycine-Phe-Arg 4-nitroanilide + H2O

H-D-Pro-hexahydrotyrosyl-Arg 4-nitroanilide + H2O

Human blood coagulation factor X + H2O

Human blood coagulation factor Xa

enzyme appears to act as substitute for both factor VIIIa and IXa by activating factor X

i.e. EC 3.4.21.6

Human blood coagulation factor XIII + H2O

Activated human blood coagulation factor XIII

activates factor XIII

human fibrinogen beta-chain + H2O

low activity

human prothrombin + H2O

moderate activity

integrin alpha-6 + H2O

higher activity

kininogen-1 + H2O

higher activity

Nalpha-benzoyl-L-Arg 4-nitroanilide + H2O

Ovophis okinavensis

29369

Nalpha-Benzoyl-L-Arg ethyl ester + H2O

Tosyl-Gly-Pro-Arg 4-nitroanilide + H2O

Tosyl-Gly-Pro-Lys 4-nitroanilide + H2O

Tosyl-L-Arg methyl ester + H2O

2 entries

Tripeptide nitroanilide derivatives + H2O

Tripeptide + 4-nitroaniline

poor substrates