Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.2.2.8: ribosylpyrimidine nucleosidase

This is an abbreviated version!
For detailed information about ribosylpyrimidine nucleosidase, go to the full flat file.

Word Map on EC 3.2.2.8

Reaction

a pyrimidine nucleoside
+
H2O
=
D-ribose
 +
a pyrimidine base

Synonyms

CU-NH, cytidine-uridine nucleoside hydrolase, cytidine-uridine-preferring nucleoside hydrolase, LBRM_18_1610, More, N-ribohydrolase, N-ribosylpyrimidine nucleosidase, N-ribosylpyrimidine ribohydrolase, NH, NSH1, nucleosidase, pyrimidine, nucleoside hydrolase, pyrimidine nucleosidase, pyrimidine nucleoside hydrolase, pyrimidine-specific nucleoside hydrolase, ribonucleoside hydrolase 1, rih1, RihA, RihB, SsCU-NH, SSO0505, URH1, uridine-ribohydrolase 1, YbeK, YeiK

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.8 ribosylpyrimidine nucleosidase

Inhibitors

Inhibitors on EC 3.2.2.8 - ribosylpyrimidine nucleosidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3,4-diaminophenyl-D-iminoribitol
-
competitive, the ligand can bind at the active site in two distinct orientations, binding structure, overview
4,6-Dihydroxy-1-beta-D-ribofuranosylpyrazolo-(3,4-d) pyrimidine
-
-
4-Hydroxyl-1-beta-D-ribofuranosylpyrazolo-(3,4-d) pyrimidine
-
-
4-Methylthio-1-beta-D-ribofuranosylpyrazolo-(3,4-d)pyrimidine
-
-
4-Thio-1-beta-D-ribofuranosylpyrazolo-(3,4-d)pyrimidine
-
-
adenosine
AgCl
-
at 1 mM: inhibition less than 10%
CaCl2
-
at 1 mM, inhibition less than 10%
CdCl2
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
CoCl2
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
CuCl2
-
at 1 mM: inhibition less than 10%
cytidine
-
at 6.25 mM, competitive inhibitor for uridine hydrolysis
EDTA
-
at 1 mM: inhibits uridine hydrolysis by 50%
FeCl3
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
FeSO4
-
at 1 mM: inhibition less than 10%
guanosine
-
-
HgCl2
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
Inosine
-
at 6.25 mM, competitive inhibitor for uridine hydrolysis
MgCl2
-
at 1 mM: inhibition less than 10%
MnSO4
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
NH4Cl
-
at 1 mM: inhibition less than 10%
ZnCl2
-
at 1 mM: inhibition ranging from 40-95%, at 0.01 mM: inhibition less than 10%
additional information
-
poor inhibitors
-