1.14.11.79: protein-L-histidine (3S)-3-hydroxylase
This is an abbreviated version!
For detailed information about protein-L-histidine (3S)-3-hydroxylase, go to the full flat file.
Reaction
Synonyms
C14orf169, MAPJD, MDIG, MINA, MINA53, NO52, NO66, protein histidyl hydroxylase, RIOX1, RIOX2
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.14.11.79 - protein-L-histidine (3S)-3-hydroxylase
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REACTION DIAGRAM
[Rpl27a]-L-histidine39 + 2-oxoglutarate + O2
[Rpl27a]-(3S)-3-hydroxy-L-histidine39 + succinate + CO2
[Rpl8]-L-histidine216 + 2-oxoglutarate + O2
[Rpl8]-(3S)-3-hydroxy-L-histidine216 + succinate + CO2
[Rpl27a]-(3S)-3-hydroxy-L-histidine39 + succinate + CO2
substrate i.e. 60S ribosomal protein
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-
?
[Rpl27a]-L-histidine39 + 2-oxoglutarate + O2
[Rpl27a]-(3S)-3-hydroxy-L-histidine39 + succinate + CO2
substrate i.e. large ribosomal subunit protein
-
-
?
[Rpl8]-(3S)-3-hydroxy-L-histidine216 + succinate + CO2
substrate i.e. 60S ribosomal protein
-
-
?
[Rpl8]-L-histidine216 + 2-oxoglutarate + O2
[Rpl8]-(3S)-3-hydroxy-L-histidine216 + succinate + CO2
substrate i.e. 60S ribosomal protein
-
-
?
?
-
HXHR is the preferred motif for hydroxylation
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additional information
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HXHR is the preferred motif for hydroxylation
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additional information
?
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NHXH is the preferred motif for hydroxylation
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additional information
?
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NHXH is the preferred motif for hydroxylation
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