1.1.1.387: L-serine 3-dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about L-serine 3-dehydrogenase (NAD+), go to the full flat file.

Reaction

2-aminomalonate semialdehyde
=
2-aminoacetaldehyde
+
CO2

Synonyms

NAD+-dependent L-serine dehydrogenase, PA0743

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.387 L-serine 3-dehydrogenase (NAD+)

Engineering

Engineering on EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D247A
inactive protein
K171A
inactive protein
K246A
inactive protein
N175A
mutant enzyme with very low activity
S122A
mutant enzyme with very low activity
T96A
mutant enzyme with very low activity
W214A
inactive protein
Y219A
mutant enzyme with very low activity