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Information on EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)

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IUBMB Comments
The enzyme, purified from the bacterium Pseudomonas aeruginosa, also shows activity with L-threonine (cf. EC 1.1.1.103, L-threonine 3-dehydrogenase). The enzyme has only very low activity with NADP+ [cf. EC 1.1.1.276, serine 3-dehydrogenase (NADP+)].
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The expected taxonomic range for this enzyme is: Pseudomonas aeruginosa
Synonyms
NAD+-dependent L-serine dehydrogenase, PA0743, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-aminomalonate semialdehyde = 2-aminoacetaldehyde + CO2
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L-serine + NAD+ = 2-aminoacetaldehyde + CO2 + NADH + H+
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L-serine + NAD+ = 2-aminomalonate semialdehyde + NADH + H+
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