1.1.1.387: L-serine 3-dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about L-serine 3-dehydrogenase (NAD+), go to the full flat file.

Reaction

2-aminomalonate semialdehyde
=
2-aminoacetaldehyde
+
CO2

Synonyms

NAD+-dependent L-serine dehydrogenase, PA0743

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.387 L-serine 3-dehydrogenase (NAD+)

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-serine + NAD+
?
show the reaction diagram
the enzyme might be involved in serine/threonine degradation. Since growth experiments with various nitrogen and carbon sources (including L-serine) reveal no difference between the Pseudomonas aeruginosa wild-type and PA0743 deletion strains, it is suggested hat this organism might contain other (complementing) serine dehydrogenases
-
-
?