1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

This is an abbreviated version, for detailed information about dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase, go to the full flat file.

Reaction

dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose
+
NADP+
=
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose
+
NADPH
+
H+

Synonyms

DTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase, dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose 3-oxidoreductase, dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase, jadP, KijD10, NDP-hexose 3-ketoreductase, OleW, SpnN

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

Reference

Reference on EC 1.1.1.384 - dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kubiak, R.L.; Holden, H.M.
Combined structural and functional investigation of a C-3''-ketoreductase involved in the biosynthesis of dTDP-L-digitoxose
Biochemistry
50
5905-5917
2011
Actinomadura kijaniata, Actinomadura kijaniata (B3TMR8)
Manually annotated by BRENDA team
Aguirrezabalaga, I.; Olano, C.; Allende, N.; Rodriguez, L.; Brana, A.; Mendez, C.; Salas, J.
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus
Antimicrob. Agents Chemother.
44
1266-1275
2000
Streptomyces antibioticus (Q9RR32)
Manually annotated by BRENDA team
Hong, L.; Zhao, Z.; Melancon III, C.; Zhang, H.; Liu, H.
In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa
J. Am. Chem. Soc.
130
4954-4967
2008
Saccharopolyspora spinosa (Q9ALN5)
Manually annotated by BRENDA team
Wang, L.; White, R.; Vining, L.
Biosynthesis of the dideoxysugar component of jadomycin B: Genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone
Microbiology
148
1091-1103
2002
Streptomyces venezuelae (Q939Q8)
Manually annotated by BRENDA team