1.1.1.245: cyclohexanol dehydrogenase
This is an abbreviated version!
For detailed information about cyclohexanol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.245
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1.1.1.245
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cyclohexanone
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monooxygenase
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cycloalkanes
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ncimb
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cyclopentanone
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acinetobacter
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baeyer-villiger
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alicyclic
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xanthobacter
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acidovorax
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lactones
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synthesis
- 1.1.1.245
- cyclohexanone
- monooxygenase
-
cycloalkanes
-
ncimb
- cyclopentanone
- acinetobacter
-
baeyer-villiger
-
alicyclic
- xanthobacter
- acidovorax
- lactones
- synthesis
Reaction
Synonyms
alcohol dehydrogenase, CHXON, cyclohexanol dehydrogenase II, dehydrogenase, cyclohexanol, SSADH
ECTree
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Engineering
Engineering on EC 1.1.1.245 - cyclohexanol dehydrogenase
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N249Y
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mutant N249Y displays non-cooperative behavious in coenzyme binding under the same experimental conditions used for the wild-type enzyme (that exhibits linearity of NAD(H) binding at pH 9.8 and at moderate ionic strength, in addition to positive cooperativity at pH 7.8 and 6.8, and at pH 9.8 in the presence of salt. NADH binding is positively cooperative below 20°C and negatively cooperative at 4050°)