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1.1.1.245: cyclohexanol dehydrogenase

This is an abbreviated version!
For detailed information about cyclohexanol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.245

Reaction

Cyclohexanol
+
NAD+
=
cyclohexanone
+
NADH
+
H+

Synonyms

alcohol dehydrogenase, CHXON, cyclohexanol dehydrogenase II, dehydrogenase, cyclohexanol, SSADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.245 cyclohexanol dehydrogenase

Engineering

Engineering on EC 1.1.1.245 - cyclohexanol dehydrogenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
N249Y
-
mutant N249Y displays non-cooperative behavious in coenzyme binding under the same experimental conditions used for the wild-type enzyme (that exhibits linearity of NAD(H) binding at pH 9.8 and at moderate ionic strength, in addition to positive cooperativity at pH 7.8 and 6.8, and at pH 9.8 in the presence of salt. NADH binding is positively cooperative below 20°C and negatively cooperative at 40–50°)