1.1.1.159: 7alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

Synonyms

7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid, J-1-1, NADP(H)-dependent 7alpha-HSDH, NADP(H)-dependent 7alpha-hydroxysteroid dehydrogenase, NADP+-dependent 7alpha-HSDH, nicotinamide adenine dinucleotide phosphate-dependent 7alpha-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.159 7alpha-hydroxysteroid dehydrogenase

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Results

in table

9

Activating Compound

1020

AA Sequence

8

Application

1

CAS Registry Number

13

Cloned(Commentary)

40

Cofactor

4

Crystallization (Commentary)

33

Engineering

12

General Information

4

General Stability

37

Inhibitors

13

KCat/KM [mM/s]

61

KM Value [mM]

10

Metals/Ions

16

Molecular Weight [Da]

20

Natural Substrates/ Products (Substrates)

57

Organism

3

Pathway

26

PDB ID

16

pH Optimum

3

pH Range

4

pH Stability

1

pI Value

17

Purification (Commentary)

4

Reaction

3

Reaction Type

45

Reference

2

Source Tissue

31

Specific Activity [micromol/min/mg]

4

Storage Stability

133

Substrates and Products (Substrate)

15

Subunits

38

Synonyms

1

Systematic Name

5

Temperature Optimum [°C]

1

Temperature Range [°C]

15

Temperature Stability [°C]

24

Turnover Number [1/s]