2.7.1.52: fucokinase
This is an abbreviated version!
For detailed information about fucokinase, go to the full flat file.
Word Map on EC 2.7.1.52
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2.7.1.52
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salvage
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fucosyltransferase
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3hfucose
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reutilization
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gdp-alpha-d-mannose
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gdp-beta-l-fucose
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synthesis
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analysis
- 2.7.1.52
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salvage
-
fucosyltransferase
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3hfucose
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reutilization
- gdp-alpha-d-mannose
- gdp-beta-l-fucose
- synthesis
- analysis
Reaction
Synonyms
ATP:6-deoxy-beta-L-galactose 1-phosphotransferase, ATP:6-deoxy-L-galactose 1-phospho transferase, Fkgp, FKP, fucokinase, fucokinase/L-fucose-1-P-guanylyltransferase, fucokinase:GDP-fucose pyrophosphorylase, fucose kinase, Fuk, kinase, fuco- (phosphorylating), L-fucokinase, L-fucokinase/guanosine 5'-diphosphate-L-fucose pyrophosphorylase, L-fucokinase/guanosine-5'-diphosphate-Fuc pyrophosphorylase, L-fucokinase:GDP-fucose pyrophosphorylase, L-fucose kinase, L-fucose kinase/GDP-L-fucose pyrophosphorylase, More
ECTree
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Engineering
Engineering on EC 2.7.1.52 - fucokinase
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G133A
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mutation abolishes GDP-L-fucose diphosphorylase activity, hardly affects fucokinase activity
G830A
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mutation reduces fucokinase activity by more than 90%, while preserving the GDP-L-fucose diphosphorylase activity
G757A
the mutant has greatly reduced fucokinase activity compared to the wild type enzyme
G902A
the mutant has greatly reduced fucokinase activity compared to the wild type enzyme
T602A
the mutant has greatly reduced fucokinase activity compared to the wild type enzyme
additional information
deletion mutant lacking the first 363 amino acids of the N-terminus expressed in Escherichia coli BL21 cells display fucokinase activity
additional information
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deletion mutant lacking the first 363 amino acids of the N-terminus expressed in Escherichia coli BL21 cells display fucokinase activity