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2.6.1.26: thyroid-hormone transaminase

This is an abbreviated version!
For detailed information about thyroid-hormone transaminase, go to the full flat file.

Reaction

L-3,5,3'-triiodothyronine
+
2-oxoglutarate
=
3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropanoate
+
L-glutamate

Synonyms

3,5-dinitrotyrosine transaminase, aminotransferase, thyroid hormone

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.26 thyroid-hormone transaminase

pH Range

pH Range on EC 2.6.1.26 - thyroid-hormone transaminase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7 - 8.6
-
pH 7.0: 30% of maximal activity with L-triiodothyronine, 15% of maximal activity with 3,5-dinitro-L-tyrosine, pH 7.4-8.6: maximal activity with triiodothyronine and 3,5-dinitro-L-tyrosine