2.5.1.97: pseudaminic acid synthase

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For detailed information about pseudaminic acid synthase, go to the full flat file.

Reaction

Synonyms

NeuB3, PseG, PseI

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.97 pseudaminic acid synthase

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Results	in table
1889	AA Sequence
2	Cloned(Commentary)
1	General Information
2	KM Value [mM]
5	Metals/Ions
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
4	Pathway
4	PDB ID
1	pH Optimum
2	Purification (Commentary)
1	Reaction
2	Reference
5	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

General Information

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General Information on EC 2.5.1.97 - pseudaminic acid synthase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Campylobacter jejuni

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Campylobacter jejuni and Campylobacter coli are the main causes of bacterial diarrhea worldwide. In all of these pathogenic organisms, the flagellin proteins are heavily glycosylated with pseudaminic acid (the product of the PseI catalyzed reaction). The presence of 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid is required for the proper development of the flagella and is thereby necessary for motility in, and invasion of, the host

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