2.3.3.9: malate synthase

This is an abbreviated version!
For detailed information about malate synthase, go to the full flat file.

Reaction

Synonyms

EC 4.1.3.2, GCE, GCE(13-573), glcB, glyoxylate cycle enzyme, glyoxylate transacetase, glyoxylic transacetase, L-malate glyoxylate-lyase (CoA-acetylating), malate synthase, malate synthase 1, malate synthase A, malate synthase G, malate synthase H, malate synthetase, malic synthetase, malic-condensing enzyme, MLS, MSA, MSG, MSH, SSO1334

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.3 Acyl groups converted into alkyl groups on transfer

                2.3.3.9 malate synthase

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Results	in table
2	Activating Compound
26198	AA Sequence
1	Application
1	CAS Registry Number
25	Cloned(Commentary)
6	Crystallization (Commentary)
10	Expression
4	General Information
10	General Stability
7	IC50 Value
99	Inhibitors
43	Ki Value [mM]
71	KM Value [mM]
20	Localization
51	Metals/Ions
78	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
110	Organism
13	Pathway
70	PDB ID
22	pH Optimum
12	pH Range
9	pH Stability
1	pI Value
5	Posttranslational Modification
20	Protein Variants
45	Purification (Commentary)
7	Reaction
3	Reaction Type
105	Reference
1	Renatured (Commentary)
37	Source Tissue
37	Specific Activity [micromol/min/mg]
7	Storage Stability
109	Substrates and Products (Substrate)
61	Subunits
66	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
8	Temperature Range [°C]
18	Temperature Stability [°C]
13	Turnover Number [1/s]

pH Stability

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pH Stability on EC 2.3.3.9 - malate synthase

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pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

1 - 2

Pseudomonas aeruginosa

-

1 h preincubation: about 5% activity

702873

11

Pseudomonas aeruginosa

-

1 h preincubation: 90% activity

702873

5

Pseudomonas aeruginosa

-

1 h preincubation: about 5% activity

702873

5.5

Pinus densiflora

-

4°C, 12 h, about 60% loss of activity, enzyme form MSH

638472

6

Pinus densiflora

-

4°C, 12 h, about 90% loss of activity, enzyme form MSH

638472

6 - 7

Pseudomonas aeruginosa

-

1 h preincubation: 100% activity

702873

7

Streptomyces arenae

-

inactive at pH 7.0 and below

638491

7 - 8

Pinus densiflora

-

4°C, 12 h, stable, enzyme forms MSL and MSH

638472

9

Pinus densiflora

-

4°C, 12 h, about 50% loss of activity, enzyme form MSL, about 40% loss of activity of enzyme form MSH

638472