2.3.2.25: N-terminal E2 ubiquitin-conjugating enzyme

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For detailed information about N-terminal E2 ubiquitin-conjugating enzyme, go to the full flat file.

Word Map on EC 2.3.2.25

2.3.2.25

ubch5a

finger

polyubiquitination

monoubiquitination

proteasome-dependent

ring-finger

autoubiquitination

ube2e2

isopeptide

ubiquitin-specific

polyglutamine

isg15

spinocerebellar

ataxin-1

cdc34

Reaction

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine

[acceptor protein]-N-terminal-amino acid

[E1 ubiquitin-activating enzyme]-L-cysteine

N-terminal-ubiquitinyl-[acceptor protein]

Synonyms

E2 Ube2w, E2 ubiquitin-conjugating enzyme, Ubc16, UbcH6, UBE2E1, UBE2O, UBE2W, ubiquitin conjugating enzyme, ubiquitin conjugating enzyme E2, ubiquitin-conjugating enzyme (E2), ubiquitin-conjugating enzyme E2, ubiquitin-protein ligase W

ECTree

2 Transferases

2.3 Acyltransferases

2.3.2 Aminoacyltransferases

2.3.2.25 N-terminal E2 ubiquitin-conjugating enzyme

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Results	in table
28	AA Sequence
2	Application
5	Cloned(Commentary)
207	Disease/ Diagnostics
24	General Information
7	Localization
1	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
11	Organism
2	pH Optimum
10	Protein Variants
1	Purification (Commentary)
4	Reaction
11	Reference
14	Source Tissue
29	Substrates and Products (Substrate)
2	Subunits
28	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.2.25 - N-terminal E2 ubiquitin-conjugating enzyme

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S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid

[E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein]

6 entries

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [huntingtin]-N-terminal-amino acid

[E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[huntingtin]

2 entries

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [NLRP1B]-N-terminal-amino acid

[E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[NLRP1B]

Mus musculus

Q6ZPJ3

NLRP1B inflammasome is ubiquitinylated at the N-terminal Leu248

759122