Disease on EC 2.3.2.25 - N-terminal E2 ubiquitin-conjugating enzyme
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Adenocarcinoma of Lung
Expression of UBE2C in lung adenocarcinoma based on database analysis and its clinical significance.
Adenocarcinoma of Lung
High ubiquitin conjugating enzyme E2 T mRNA expression and its prognostic significance in lung adenocarcinoma: A study based on the TCGA database.
Adenocarcinoma of Lung
Ubiquitin Conjugating Enzyme E2 H (UBE2H) Is Linked to Poor Outcomes and Metastasis in Lung Adenocarcinoma.
African Swine Fever
An ARID family protein binds to the African swine fever virus encoded ubiquitin conjugating enzyme, UBCv1.
Alzheimer Disease
A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3.
Alzheimer Disease
Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer's Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7).
Autoimmune Diseases
The haplotype of UBE2L3 gene is associated with Hashimoto's thyroiditis in a Chinese Han population.
Breast Neoplasms
Identifying breast cancer subtypes associated modules and biomarkers by integrated bioinformatics analysis.
Breast Neoplasms
Inhibition of ubiquitin conjugating enzyme UBE2C reduces proliferation and sensitizes breast cancer cells to radiation, doxorubicin, tamoxifen and letrozole.
Breast Neoplasms
Prognostic value of ubiquitin E2 UBE2W and its correlation with tumor-infiltrating immune cells in breast cancer.
Breast Neoplasms
Stromal cell extracellular vesicular cargo mediated regulation of breast cancer cell metastasis via ubiquitin conjugating enzyme E2 N pathway.
Carcinogenesis
BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis.
Carcinogenesis
Combined elevation of AURKB and UBE2C predicts severe outcomes and therapy resistance in glioma.
Carcinogenesis
Identification of key candidate genes and pathways in endometrial cancer: Evidence from bioinformatics analysis.
Carcinogenesis
Inhibiting ubiquitin conjugating enzyme E2 N by microRNA-590-3p reduced cell growth of cervical carcinoma.
Carcinogenesis
[Selecting functional siRNA target sites of hUBE2W based on H1-U6 dual promoter RNAi plasmid]
Carcinoma
Inhibiting ubiquitin conjugating enzyme E2 N by microRNA-590-3p reduced cell growth of cervical carcinoma.
Carcinoma
Overexpression of UBE2C in esophageal squamous cell carcinoma tissues and molecular analysis.
Carcinoma, Hepatocellular
The ménage à trois of autophagy, lipid droplets and liver disease.
Colitis
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Colitis, Ulcerative
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Crohn Disease
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Endometrial Neoplasms
MLN4924 inhibits cell proliferation by targeting the activated neddylation pathway in endometrial carcinoma.
Esophageal Squamous Cell Carcinoma
Overexpression of UBE2C in esophageal squamous cell carcinoma tissues and molecular analysis.
Fanconi Anemia
UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2.
Glioma
Combined elevation of AURKB and UBE2C predicts severe outcomes and therapy resistance in glioma.
Huntington Disease
The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin.
Hypersensitivity
Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage.
Inflammatory Bowel Diseases
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Leukemia
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Leukemia, T-Cell
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Liver Diseases
BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis.
Neoplasm Metastasis
Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis.
Neoplasm Metastasis
Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1?/VEGFA signalling in hepatocellular carcinoma.
Neoplasm Metastasis
Stromal cell extracellular vesicular cargo mediated regulation of breast cancer cell metastasis via ubiquitin conjugating enzyme E2 N pathway.
Neoplasm Metastasis
Ubiquitin Conjugating Enzyme E2 H (UBE2H) Is Linked to Poor Outcomes and Metastasis in Lung Adenocarcinoma.
Neoplasms
BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis.
Neoplasms
Combined elevation of AURKB and UBE2C predicts severe outcomes and therapy resistance in glioma.
Neoplasms
High ubiquitin conjugating enzyme E2 T mRNA expression and its prognostic significance in lung adenocarcinoma: A study based on the TCGA database.
Neoplasms
Inhibiting ubiquitin conjugating enzyme E2 N by microRNA-590-3p reduced cell growth of cervical carcinoma.
Neoplasms
Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1?/VEGFA signalling in hepatocellular carcinoma.
Neoplasms
Manipulation of the ubiquitin-proteasome pathway in cachexia: pentoxifylline suppresses the activation of 20S and 26S proteasomes in muscles from tumor-bearing rats.
Neoplasms
miRNA?101?3p.1 as an independent diagnostic biomarker aggravates chronic obstructive pulmonary disease via activation of the EGFR/PI3K/AKT signaling pathway.
Neoplasms
Oncogene UBE2I enhances cellular invasion, migration and proliferation abilities via autophagy-related pathway resulting in poor prognosis in hepatocellular carcinoma.
Neoplasms
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Neoplasms
Sumoylation of transcription factor ETV1 modulates its oncogenic potential in prostate cancer.
Neoplasms
The Positive Correlations between the Expression of Histopathological Ubiquitin-Conjugating Enzyme 2O Staining and Prostate Cancer Advancement.
Neoplasms
UBE2C Drives Human Cervical Cancer Progression and Is Positively Modulated by mTOR.
Neoplasms
UBE2C is involved in the functions of ECRG4 on esophageal squamous cell carcinoma.
Neoplasms
UBE2C mRNA expression controlled by miR-300 and HuR determines its oncogenic role in gastric cancer.
Neoplasms
Ube2S regulates Wnt/?-catenin signaling and promotes the progression of non-small cell lung cancer.
Neoplasms
Ubiquitin Conjugating Enzyme E2 H (UBE2H) Is Linked to Poor Outcomes and Metastasis in Lung Adenocarcinoma.
Neoplasms
Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation.
Neoplasms
Uev1A-Ubc13 promotes colorectal cancer metastasis through regulating CXCL1 expression via NF-?B activation.
Non-alcoholic Fatty Liver Disease
The ménage à trois of autophagy, lipid droplets and liver disease.
Osteoarthritis
Ubiquitin conjugating enzyme E2 M promotes apoptosis in osteoarthritis chondrocytes via Wnt/?-catenin signaling.
Prostatic Neoplasms
miR-499a inhibits the proliferation and apoptosis of prostate cancer via targeting UBE2V2.
Prostatic Neoplasms
Sumoylation of transcription factor ETV1 modulates its oncogenic potential in prostate cancer.
Retinoblastoma
An ARID family protein binds to the African swine fever virus encoded ubiquitin conjugating enzyme, UBCv1.
Retinoblastoma
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Sarcoma
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Sarcoma
Using mRNA deep sequencing to analyze differentially expressed genes during Panax notoginseng saponin treatment of ischemic stroke.
Sepsis
Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.
Stomach Neoplasms
UBE2C mRNA expression controlled by miR-300 and HuR determines its oncogenic role in gastric cancer.
Triple Negative Breast Neoplasms
Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib.
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