2.3.2.11: alanylphosphatidylglycerol synthase

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For detailed information about alanylphosphatidylglycerol synthase, go to the full flat file.

Reaction

Synonyms

A-PG synthase, A-PGS, Ala-PG synthase, alanyl phosphatidylglycerol synthetase, alanyl-phosphatidylglycerol synthase, alanylphosphatidylglycerol synthase, Cg1103 protein, MprF1, O-alanylphosphatidylglycerol synthase, synthase, O-alanylphosphatidylglycerol

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.2 Aminoacyltransferases

                2.3.2.11 alanylphosphatidylglycerol synthase

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Results	in table
1	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
1	Crystallization (Commentary)
1	Expression
1	General Information
1	General Stability
2	Inhibitors
4	Localization
1	Metals/Ions
4	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
8	Organism
2	PDB ID
2	pH Optimum
33	Protein Variants
3	Purification (Commentary)
1	Reaction
3	Reaction Type
8	Reference
2	Storage Stability
18	Substrates and Products (Substrate)
2	Subunits
18	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

General Information

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General Information on EC 2.3.2.11 - alanylphosphatidylglycerol synthase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Clostridium perfringens

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MprF1-mediated alanyl-phosphatidylglycerol production in Staphylococcus aureus does not affect susceptibility to gallidermin and nisin and leads to only a minor decrease in daptomycin susceptibility. Coexpression of the enzyme with flippase domains of lysyl-phosphatidylglycerol synthesizing MprF proteins leads to a wild type level of daptomycin susceptibility

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