2.3.1.97: glycylpeptide N-tetradecanoyltransferase

This is an abbreviated version!
For detailed information about glycylpeptide N-tetradecanoyltransferase, go to the full flat file.

Word Map on EC 2.3.1.97

2.3.1.97

myristate

n-myristoylation

albicans

leishmania

octapeptide

co-translational

pp60src

14-carbon

nonmyristoylated

medicine

benzofuran

drug development

molecular biology

synthesis

analysis

Reaction

an N-terminal-N-tetradecanoylglycyl-[protein]

Synonyms

CaNMT, cell division control protein 72, dipeptide N-myristoyltransferase 2, glycylpeptide N-tetradecanoyltransferase, glycylpeptide N-tetradecanoyltransferase 1, glycylpeptide N-tetradecanoyltransferase 2, HsNMT1, HsNMT2, LmNMT, More, myristoyl-CoA-protein N-myristoyltransferase, myristoyl-CoA: protein N-myristoyltransferase, myristoyl-CoA:protein N-myristoyltransferase, myristoyl-CoA:protein N-myristoyltransferase 1, myristoyl-CoA:protein N-myristoyltransferase 2, myristoyl-CoA:protein N-myristoyltransferase type 2, myristoyl-coenzyme A:protein N-myristoyl transferase, myristoyl-coenzyme A:protein N-myristoyltransferase, myristoylating enzymes, myristoyltransferase, myristoyltransferase type 1, myristoyltransferase, protein N-, N-myristoyl transferase, N-myristoyltransferase, N-myristoyltransferase 1, N-myristoyltransferase 2, NMT, NMT 1, NMT 2, NMT-1, NMT-2, NMT1, Nmt1p, NMT2, peptide N-myristoyltransferase, peptide N-myristoyltransferase 1, peptide N-myristoyltransferase 2, protein N-myristoyltransferase, PVX_085815, TbNMT, type I N-myristoyltransferase, type II N-myristoyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.97 glycylpeptide N-tetradecanoyltransferase

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Results	in table
18	Activating Compound
5785	AA Sequence
24	Application
1	CAS Registry Number
45	Cloned(Commentary)
12	Crystallization (Commentary)
296	Disease/ Diagnostics
2	Expression
30	General Information
138	IC50 Value
560	Inhibitors
14	kcat/KM [mM/s]
79	Ki Value [mM]
102	KM Value [mM]
42	Localization
3	Metals/Ions
42	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
187	Organism
3	Oxidation Stability
244	PDB ID
28	pH Optimum
2	pH Range
1	pI Value
2	Posttranslational Modification
51	Protein Variants
41	Purification (Commentary)
37	Reaction
4	Reaction Type
174	Reference
1	Renatured (Commentary)
123	Source Tissue
31	Specific Activity [micromol/min/mg]
4	Storage Stability
289	Substrates and Products (Substrate)
37	Subunits
255	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
5	Temperature Stability [°C]
23	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.3.1.97 - glycylpeptide N-tetradecanoyltransferase

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acetonitrile

Homo sapiens

2.5fold activation at 5% v/v

487764

deoxycholate

2 entries

dimethyl ammonium chloride

Homo sapiens

6.5fold increase in activity with Gly-Ser-Ser-Lys-Ser-Lys-Pro-Lys-Arg as substrate, 2.5fold increase with Gly-Asn-Ala-Ala-Ala-Ala-Lys-Lys-Arg-Arg

Dimethylsulfoxide

EDTA

ethanol

5fold activation at 10% v/v

487764

L-histidine

Homo sapiens

activation in a concentration dependent manner

487770

N-myristoyltransferase activator NAF45

3 entries

SDS

Homo sapiens

3.2fold activation at 1.73 mM

487764

Tris

Homo sapiens

activates about 2.5fold at 225 mM compared to 40 mM

487764

Triton 770

Mus musculus

2% w/v, activation by pretreatment

487744

Triton X-100

Arabidopsis thaliana

Q9LTR9

25% activation at 0.1%

487773