Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.206: 3,5,7-trioxododecanoyl-CoA synthase

This is an abbreviated version!
For detailed information about 3,5,7-trioxododecanoyl-CoA synthase, go to the full flat file.

Word Map on EC 2.3.1.206

Reaction

3 malonyl-CoA +

hexanoyl-CoA
= 3 CoA +
3,5,7-trioxododecanoyl-CoA
+ 3 CO2

Synonyms

OLA synthase, olivetol synthase, olivetol-forming PKS, OLS, PKS, polyketide synthase, tetraketide synthase, TKS, type III PKS, type III polyketide synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase

Cloned

Cloned on EC 2.3.1.206 - 3,5,7-trioxododecanoyl-CoA synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
expression of TKS in Escherichia coli, transient co-expression of fluorescent-labeled TKS and OAC in Nicotiana benthamiana leaves shows that TKS and OAC, which lack predicted signal peptides, are both localized to the cytoplasm. Yeast cultures expressing TKS and OAC and fed sodium hexanoate produce olivetolic acid and olivetol in the medium but no alpha-pyrones
-
gene pks, cDNA and amino acid sequence determination and analysis, overexpression of His-tagged PKS in Escherichia coli strain M15
-
recombinant expression of the C-terminally His-tagged enzyme
-