2.3.1.206: 3,5,7-trioxododecanoyl-CoA synthase

This is an abbreviated version!
For detailed information about 3,5,7-trioxododecanoyl-CoA synthase, go to the full flat file.

Word Map on EC 2.3.1.206

2.3.1.206

starter

chalcone

pyrones

triketide

condensations

alkylresorcinols

4-coumaroyl-coa

1,3,6,8-tetrahydroxynaphthalene

pentaketide

resorcinol

cys-his-asn

benzalacetone

octaketide

flaviolin

chs-like

huperzia

alpha-pyrones

olivetolic

arborescens

hexaketide

resorcylic

coa-linked

precursor-directed

n-methylanthraniloyl-coa

synthesis

Reaction

3 malonyl-CoA +

= 3 CoA +

+ 3 CO2

Synonyms

OLA synthase, olivetol synthase, olivetol-forming PKS, OLS, PKS, polyketide synthase, tetraketide synthase, TKS, type III PKS, type III polyketide synthase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase

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Results	in table
1	AA Sequence
1	Application
5	Cloned(Commentary)
1	Crystallization (Commentary)
8	General Information
2	kcat/KM [mM/s]
3	KM Value [mM]
1	Localization
4	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
8	Organism
3	Pathway
8	PDB ID
4	pH Optimum
1	pI Value
1	Protein Variants
2	Purification (Commentary)
1	Reaction
8	Reference
17	Source Tissue
1	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
3	Subunits
18	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Turnover Number [1/s]

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Reference on EC 2.3.1.206 - 3,5,7-trioxododecanoyl-CoA synthase

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706171

Flores-Sanchez, I.J.; Verpoorte, R.

PKS activities and biosynthesis of cannabinoids and flavonoids in Cannabis sativa L. plants

Plant Cell Physiol.

1767-1782

2008

Cannabis sativa

18854334

719492

Taura, F.; Tanaka, S.; Taguchi, C.; Fukamizu, T.; Tanaka, H.; Shoyama, Y.; Morimoto, S.

Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway

FEBS Lett.

583

2061-2066

2009

Cannabis sativa

19454282

720721

Raharjo, T.; Chang, W.; Verberne, M.; Peltenburg-Looman, A.; Linthorst, H.; Verpoorte, R.

Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa

Plant Physiol. Biochem.

291-297

2004

Cannabis sativa, Cannabis sativa Four-way

15120113

720760

Raharjo, T.; Chang, W.; Choi, Y.; Peltenburg-Looman, A.; Verpoorte, R.

Olivetol as product of a polyketide synthase in Cannabis sativa L

Plant Sci.

166

381-385

2004

Cannabis sativa

100138838

720934

Gagne, S.; Stout, J.; Liu, E.; Boubakir, Z.; Clark, S.; Page, J.

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides

Proc. Natl. Acad. Sci. USA

109

12811-12816

2012

Cannabis sativa

22802619

746606

Tan, Z.; Clomburg, J.M.; Gonzalez, R.

Synthetic pathway for the production of olivetolic acid in Escherichia coli

ACS Synth. Biol.

1886-1896

2018

Cannabis sativa (B1Q2B6)

29976061

756711

Kearsey, L.J.; Prandi, N.; Karuppiah, V.; Yan, C.; Leys, D.; Toogood, H.; Takano, E.; Scrutton, N.S.

Structure of the Cannabis sativa olivetol-producing enzyme reveals cyclization plasticity in type III polyketide synthases

FEBS J.

287

1511-1524

2019

Cannabis sativa (B1Q2B6)

31605668