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2.3.1.177: 3,5-dihydroxybiphenyl synthase

This is an abbreviated version!
For detailed information about 3,5-dihydroxybiphenyl synthase, go to the full flat file.

Word Map on EC 2.3.1.177

Reaction

3 malonyl-CoA +

benzoyl-CoA
= 4 CoA +
3,5-dihydroxybiphenyl
 + 4 CO2

Synonyms

biphenyl synthase, BIS, BIS1, BIS1 biphenyl synthase, BIS2, BIS3, BIS3 biphenyl synthase, BIS4, MdBIS1, MdBIS3, PcBIS1, PcBIS2

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.177 3,5-dihydroxybiphenyl synthase

Expression

Expression on EC 2.3.1.177 - 3,5-dihydroxybiphenyl synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
addition of yeast extract to the cell cultures results in a burst of reactive oxygen species, H2O2 and O2-, followed by transcriptional activation of the biphenyl synthase 1 gene BIS1. Endogenous generation of H2O2, by superoxide dismutase, rather than that of O2- is akey factor in YE-induced accumulation of biphenyl phytoalexins in cell cultures of Sorbus aucuparia
-
BIS is only expressed when plant is infected with microorganisms
-
infection with Erwinia amylovora induces the enzyme
H2FL89, H2FL90, H2FL91, JQ390521
infection with Erwinia amylovora induces the enzyme. In cell cultures of apple cultivar Cox Orange, expression of BIS2 gene is observed after the addition of an autoclaved Erwinia amylovora suspension, BIS3 protein is accumulated in the transition zone of stems in the parenchyma of the bark at the junctions between neighboring cortical parenchyma cells
H2FL89, H2FL90, H2FL91, JQ390521
the BIS3 gene is reduced in response to inoculation with Erwinia amylovora in stems of cv. Holsteiner Cox with highest transcript levels in the transition zone between necrotic and healthy tissues. In cell cultures of apple cultivar Cox Orange, expression of BIS3 gene is observed after the addition of an autoclaved Erwinia amylovora suspension, BIS3 protein is accumulated in the transition zone of stems in the parenchyma of the bark at the junctions between neighboring cortical parenchyma cells
H2FL89, H2FL90, H2FL91, JQ390521
the enzyme is induced by elicitors
the relative transcript levels increases up to 800fold in cultivar Harrow Sweet after Erwinia amylovora inoculation
the relative transcript levels increases up to 800fold in cultivar Harrow Sweet after Erwinia amylovora inoculation, in cultivars Conference and Alexander Lucas up to 1000fold
transient induction by treatment with an elicitor preparation from the scab-causing fungus, Venturia inaequalis. Expression of BIS1 is strongly upregulated within 3 h, reaches a maximum at 6 h and decreases thereafter continuously